1

Deep Cellular Bio-Regeneration

This is “skin remodeling” in a bottle—repairing damage at the source rather than just treating symptoms.

2

Structural Volumizing & Elasticity Synthesis

PDRN promotes high-density skin, effectively reversing the thinning and sagging associated with age.

3

Anti-Inflammatory & Barrier Defense

This bridges the gap between medical-grade healing and cosmetic beauty, calming the skin to produce a uniform, luminous glow.

What is PDRN?

From Aesthetic Renewal to Clinical Recovery

PDRN (Polydeoxyribonucleotide) is a bioactive complex of purified DNA fragments with an average molecular weight of 50–1500 kDa.

It is clinically recognized for its regenerative and anti-inflammatory properties and is widely used in medical aesthetics and dermatology to support tissue repair and skin rejuvenation.

How Does PDRN Work?

1. Activation of A2A Adenosine Receptors:

Promotes fibroblast proliferation

Increases collagen, elastin, and extracellular matrix production

Enhances microcirculation and skin oxygenation

Reduces inflammatory cytokines (TNF-α, IL-6, NF-κB)

2. Support of DNA Repair & Skin Renewal:

Provides nucleotides to activate the DNA salvage pathway

Accelerates cellular regeneration and tissue re-epithelialization

Helps restore damaged or photoaged skin

The Future of Regeneration.

Unlocking the body’s native healing intelligence with clinical-grade PDRN. From cellular-level skin renewal to advanced tissue recovery.

Skin Rejuvenation

In aesthetic medicine, PDRN is often referred to as a ``skin healer`` or ``bio-revitalizer.``

It functions as a signalling molecule, instructing your skin’s own cells to repair and regenerate. It actively promotes collagen synthesis, reduces inflammation, and accelerates the natural healing cascade, fundamentally restoring the skin’s biological environment.

Stimulates Collagen & Elastin

PDRN activates fibroblasts, the cells responsible for producing collagen and elastin, leading to thicker, firmer skin.

Improves Skin Texture

It helps smooth out fine lines, wrinkles, and acne scars by regenerating the skin at a cellular level.

Enhanced Hydration

It improves the skin’s moisture-retention capabilities (often used in conjunction with Hyaluronic Acid).

Pore Size Reduction

By regulating oil production and tightening the skin matrix, it can minimize the appearance of pores.

Before and After

The Evolution of Rejuvenation.
Before

After

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info@epi-fusion.com
Location
Greater Toronto Area, Ontario, Canada
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Mon – Fri 9 am to 5 pm  

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